issue/ 'ɪʃjuː /

1.noun [c] 
(problem,subject) 问题

the issue of human rights
人权问题
2.noun
the issue (most important part) 要点

That's not the issue.
那不是问题所在。
3.noun [of magazine] [ newspaper] 


the latest issue of the magazine
最新一期杂志
4.noun [c] [o.f.] 
(offspring) 子女

He died without issue.
他死后无子女。
5.vt.[+rations] [ equipment] [ documents] 
发给

Who issued the travel documents?
谁签发旅行证件?
6.vt.[+statement] 
发表

We need to issue some sort of statement.
我们要发表某种声明。
7.vi.[liquid] [ sound] [ smell+] 
to issue (from) (从…)出来

to avoid the issue
回避问题
to confuse {or} cloud the issue
混淆问题
to take issue with sb
与某人争论
to make an issue of sth
把某事看得极为重要
to be at issue
在争议中的
to issue sth to sb
给某人发放某物
to issue sb with sth
给某人发放某物